How to Manage Ulcerative Colitis – Hear from a Gastroenterologist

Ulcerative colitis, also known as UC and colitis ulcerosa, is an inflammatory bowel disease (IBD) that causes chronic inflammation and ulcers in the digestive tract, mainly in the colon and rectum's innermost lining. This is one of the most common gastrointestinal conditions that the best gastroenterologist in Nashik treats. There is currently no cure for UC. However, the appropriate combination of drugs, as well as surgery if necessary, can greatly reduce symptoms and even provide patients with long-term remission.

What Treatment Options are Available

When a patient is diagnosed with Ulcerative Colitis, the most common treatment method doctors offer is medication. There are a number of drugs that can help reduce symptoms and possibly induce remission. The severity of each patient's symptoms and how they respond to treatments differ. A consultation with a gastroenterologist in Nashik will aid in determining the best treatment option.

Medicinal Treatment

Mesalamine

Mesalamine reduces inflammation by inhibiting the generation of inflammatory chemicals (cyclooxygenase and prostaglandin). This is a tried-and-true medication that doctors utilise as a first-line treatment for patients with mild to moderate illnesses.z

Immune System Suppressors

Azathioprine and mercaptopurine (6-MP) are examples of purine synthesis inhibitors. Purines are essential components of DNA and RNA. When purine synthesis is inhibited, it results in less DNA and RNA synthesis for the production of white blood cells, resulting in immunosuppression, says the gastrointestinalspecialist in Nashik. Over time, as the immune system weakens, inflammation decreases.

Biologics

Multiple biologics are currently on the market that belongs to three different pharmacological classes, implying two different modes of action. The anti-TNF-class of action includes infliximab, adalimumab, and golimumab, which have been on the market the longest. According to the top gastroenterologist in Nashik, these drugs help to repair the gut lining by reducing inflammation rapidly and effectively.

Surgical Treatment

Total-proctocolectomy, or removing the colon, is an effective treatment that is usually reserved for individuals who do not respond to treatments or have a disease that is rapidly progressing. However, there may be difficulties. Primary sclerosing cholangitis (PSC), or inflammation of the bile ducts, is a problem that can persist after surgery. Even years after the colon has been removed, this might occur as a consequence of ulcerative colitis. As a result, patients should see their gastroenterologist at least once a year to ensure that they are under observation for this.